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Article

Liquid biopsies: genotyping circulating tumor DNA.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Feb 2014

Diaz Luis A, Bardelli Alberto

Abstract excerpt

Genotyping tumor tissue in search of somatic genetic alterations for actionable information has become routine practice in clinical oncology. Although these sequence alterations are highly informative, sampling tumor tissue has significant inherent limitations; tumor tissue is a single snapshot in time, is subject to selection bias resulting from tumor heterogeneity, and can be difficult to obtain. Cell-free...

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Identifiers

PMID: 24449238
DOI: 10.1200/JCO.2012.45.2011
PMCID: PMC4820760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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