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Article

A universal computational model for predicting antigenic variants of influenza A virus based on conserved antigenic structures

6 Feb 2017

Abstract excerpt

Rapid determination of the antigenicity of influenza A virus could help identify the antigenic variants in time. Currently, there is a lack of computational models for predicting antigenic variants of some common hemagglutinin (HA) subtypes of influenza A viruses. By means of sequence analysis, we demonstrate here that multiple HA subtypes of influenza A virus undergo similar mutation patterns of HA1 protein (the...

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PMID: 28165025
DOI: 10.1038/srep42051

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