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Article

A Novel Method for Detection the Deafness-Associated Mitochondrial A1555G and C1494T Mutations.

Clinical laboratory - 1 Jan 2016

Qi Liu, Ping Liu, Xue-jun Dong, Guo-can Yang, Qing Wang, Yu Ding

Abstract excerpt

BACKGROUND: To develop a novel method for molecular detection of deafness-associated mitochondrial A1555G and C1494T mutations. METHODS: We designed four primers that specifically bind to human mitochondrial 12S rRNA. PCR amplification of DNA samples including the A1555G, C1494T, and healthy controls is performed. The products are analyzed by the electrophoresis. RESULTS: We found that the PCR products of DNA...

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PMID: 27156339
DOI: 10.7754/clin.lab.2015.150716

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