Characterization of key transcription factors as molecular signatures of HPV ‐positive and HPV ‐negative oral cancers

Abstract excerpt

Abstract Prior studies established constitutively active AP‐1, NF‐κB, and STAT3 signaling in oral cancer. Differential expression/activation of specific members of these transcription factors has been documented in HPV‐positive oral lesions that respond better to therapy. We performed a comprehensive analysis of differentially expressed, transcriptionally active members of these pivotal signaling mediators to...

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