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Proteomic analysis of oropharyngeal carcinomas reveals novel HPV‐associated biological pathways

26 Jun 2012

Abstract excerpt

Oropharyngeal carcinoma (OPC) can be classified into two equally prevalent subtypes depending on the presence of human papillomavirus (HPV). Patients with HPV-positive (HPV+) OPC represent a unique cohort with a distinct tumor biology and clinical behavior compared to HPV-negative (HPV-) OPC. Genetic studies have demonstrated chromosomal and gene expression changes associated with distinct subclasses of OPC;...

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PMID: 22733545
DOI: 10.1002/ijc.27699

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