Article
A cocktail of three virulent bacteriophages prevents Vibrio cholerae infection in animal models.
Nature communications - 1 Feb 2017
Yen Minmin, Cairns Lynne S, Camilli Andrew
Abstract excerpt
Effective prevention strategies will be essential in reducing disease burden due to bacterial infections. Here we harness the specificity and rapid-acting properties of bacteriophages as a potential prophylaxis therapy for cholera, a severely dehydrating disease caused by Vibrio cholerae. To this end, we test a cocktail of three virulent phages in two animal models of cholera pathogenesis (infant mouse and rabbit...
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