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Article

Bone marrow transplantation improves proximal tubule dysfunction in a mouse model of Dent disease.

Kidney international - 1 Apr 2017

Gabriel Sarah S, Belge Hendrica, Gassama Alkaly, Debaix Huguette, Luciani Alessandro, Fehr Thomas, Devuyst Olivier

Abstract excerpt

Dent disease is a rare X-linked tubulopathy caused by mutations in the endosomal chloride-proton exchanger (ClC-5) resulting in defective receptor-mediated endocytosis and severe proximal tubule dysfunction. Bone marrow transplantation has recently been shown to preserve kidney function in cystinosis, a lysosomal storage disease causing proximal tubule dysfunction. Here we test the effects of bone marrow...

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Source

Identifiers

PMID: 28143656
DOI: 10.1016/j.kint.2016.11.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Bone marrow transplantation improves proximal tubule dysfunction in a mouse model of Dent disease.PMID 28143656Read ↗

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