Article
Utility of serum DNA as a marker for KRAS mutations in pancreatic cancer tissue.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2000
Ako Soichiro, Nouso Kazuhiro, Kinugasa Hideaki, Dohi Chihiro, Matushita Hiroshi, Mizukawa Sho, Muro Shinichiro, Akimoto Yutaka, Uchida Daisuke, Tomoda Takeshi, Matsumoto Kazuyuki, Horiguchi Shigeru, Tsutsumi Koichiro, Kato Hironari, Okada Hiroyuki
Abstract excerpt
BACKGROUND/OBJECTIVES: The detection of cancer-specific DNA in peripheral blood, known as a liquid biopsy, has been reported recently. Most such studies have used plasma as a sample; however, whether or not serum can be used as effectively is unclear. We attempted to clarify suitable samples for detecting KRAS mutations in circulating DNA in the blood of pancreatic cancer patients using droplet digital polymerase...
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