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Article

Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisions.

Scientific reports - 30 Jan 2017

Konířová Jana, Oltová Jana, Corlett Alicia, Kopycińska Justyna, Kolář Michal, Bartůněk Petr, Zíková Martina

Abstract excerpt

Neural stem cells (NSCs) are defined by their dual ability to self-renew through mitotic cell division or differentiate into the varied neural cell types of the CNS. DISP3/PTCHD2 is a sterol-sensing domain-containing protein, highly expressed in neural tissues, whose expression is regulated by thyroid hormone. In the present study, we used a mouse NSC line to investigate what effect DISP3 may have on the...

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Source

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Identifiers

PMID: 28134287
DOI: 10.1038/srep41597
PMCID: PMC5278513

Genes

DISP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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