Article
[Predictive biomarkers of efficacy of checkpoint blockade inhibitors in cancer treatment].
Annales de pathologie - 1 Feb 2017
Duruisseaux Michaël, Lize-Dufranc Cécile, Badoual Céline, Bibeau Frédéric
Abstract excerpt
The remarkable efficacy of PD-1/PD-L1 and CTLA4 immune checkpoint inhibitors has led to numerous approvals in melanoma, non-small cell lung cancer, kidney cancer and several other cancers. Nevertheless, a response is observed in a variable proportion of patients, emphasizing the need for predictive biomarkers of efficacy of immune checkpoint inhibitors effectiveness. Several predictive biomarkers of efficacy are...
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