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Biomarkers for Checkpoint Inhibition

1 Jan 2017

Abstract excerpt

The identification of predictive biomarkers for the benefit of cancer immunotherapy is the holy grail of the burgeoning immunotherapy field. Recent work has shown that there are a core of concepts that establish the presence of an immune cell-infiltrate, an inflammatory signature of the tumor microenvironment, and the availability of target antigens defined by mutated neoantigens, as critical for the success of...

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PMID: 28561695
DOI: 10.14694/edbk_175463

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