Article
PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy.
Molecular cancer therapeutics - 1 Apr 2015
Patel Sandip Pravin, Kurzrock Razelle
Abstract excerpt
The resurgence of cancer immunotherapy stems from an improved understanding of the tumor microenvironment. The PD-1/PD-L1 axis is of particular interest, in light of promising data demonstrating a restoration of host immunity against tumors, with the prospect of durable remissions. Indeed, remarkable clinical responses have been seen in several different malignancies including, but not limited to, melanoma, lung,...
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