Article
Mixed hepatocellular cholangiocarcinoma tumors: Cholangiolocellular carcinoma is a distinct molecular entity.
Journal of hepatology - 1 May 2017
Moeini Agrin, Sia Daniela, Zhang Zhongyang, Camprecios Genis, Stueck Ashley, Dong Hui, Montal Robert, Torrens Laura, Martinez-Quetglas Iris, Fiel M Isabel, Hao Ke, Villanueva Augusto, Thung Swan N, Schwartz Myron E, Llovet Josep M
Abstract excerpt
BACKGROUND & AIMS: Mixed hepatocellular cholangiocarcinoma (HCC-CCA) is a rare and poorly understood type of primary liver cancer. We aimed to perform a comprehensive molecular characterization of this malignancy. METHODS: Gene expression profiling, DNA copy number detection, and exome sequencing using formalin-fixed samples from 18 patients with mixed HCC-CCA were performed, encompassing the whole histological...
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