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Article

Establishment of a Novel Model for Anticancer Drug Resistance in Three‐Dimensional Primary Culture of Tumor Microenvironment

1 Jan 2016

Abstract excerpt

Tumor microenvironment has been implicated in tumor development and progression. As a three‐dimensional tumor microenvironment model, air liquid interface (ALI) organoid culture from oncogene transgenic mouse gastrointestinal tissues was recently produced. However, ALI organoid culture system from tissues of colorectal cancer patients has not been established. Here, we developed an ALI organoid model from normal...

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PMID: 28119740
DOI: 10.1155/2016/7053872

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