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Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture

13 Jun 2019

Abstract excerpt

Organoid is a cell organization grown in a three-dimensional (3D) culture system which represents all characteristics of its origin. However, this organ-like structure requires supporting matrix to maintain its characteristics and functions. Matrigel, derived from mouse sarcoma, has often been used as the supporting matrix for organoids, but the result may not be desirable for clinical applications because of the...

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PMID: 31312220
DOI: 10.1155/2019/8472712

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