Article
Genomic insights into carbapenem- and colistin-resistant Klebsiella pneumoniae reveal co-occurrence of resistance and virulence determinants in India.
Indian journal of medical microbiology - 1 Jan 2026
Kansal Shubhangi, Kundu Jyoti, Sharma Vikas, Mamik Shubhneet Kaur, Soni Shivani, Angrup Archana, Biswal Manisha, Walia Kamini, Ray Pallab, Taneja Neelam
Abstract excerpt
BACKGROUND: Carbapenem- and colistin-resistant Klebsiella pneumoniae poses a major challenge to critical care due to limited therapeutic options. Combined with hypervirulence, the infections caused by multi-drug-resistant isolates become exceptionally difficult to treat, often resulting in prolon...
Topics
- Colistin
- Klebsiella pneumoniae
- Humans
- Carbapenems
- Anti-Bacterial Agents
- Virulence Factors
- India
- Klebsiella Infections
- Whole Genome Sequencing
- Drug Resistance, Multiple, Bacterial
- Genome, Bacterial
- Virulence
- Bacterial Proteins