Sickle Cell Trait and Renal Function in Hispanics in the United States: The Northern Manhattan Study.

doi:10.18865/ed.27.1.11

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Sickle Cell Trait and Renal Function in Hispanics in the United States: The Northern Manhattan Study.

Ethnicity & disease - 19 Jan 2017

Dueker Nicole D, Della-Morte David, Rundek Tatjana, Sacco Ralph L, Blanton Susan H

Abstract excerpt

Sickle cell anemia (SCA) is a common hematological disorder among individuals of African descent in the United States; the disorder results in the production of abnormal hemoglobin. It is caused by homozygosity for a genetic mutation in HBB; rs334. While the presence of a single mutation (sickle cell trait, SCT) has long been considered a benign trait, recent research suggests that SCT is associated with renal...

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PMID: 28115816
DOI: 10.18865/ed.27.1.11
PMCID: PMC5245602

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