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Article

Osmotolerance in Escherichia coli Is Improved by Activation of Copper Efflux Genes or Supplementation with Sulfur-Containing Amino Acids.

Applied and environmental microbiology - 1 Apr 2017

Xiao Mengyong, Zhu Xinna, Fan Feiyu, Xu Hongtao, Tang Jinlei, Qin Ying, Ma Yanhe, Zhang Xueli

Abstract excerpt

Improvement in the osmotolerance of Escherichia coli is essential for the production of high titers of various bioproducts. In this work, a cusS mutation that was identified in the previously constructed high-succinate-producing E. coli strain HX024 was investigated for its effect on osmotolerance. CusS is part of the two-component system CusSR that protects cells from Ag(I) and Cu(I) toxicity. Changing cusS from...

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PMID: 28115377
DOI: 10.1128/AEM.03050-16
PMCID: PMC5359503

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