Article

Enhanced microbiota profiling in patients with quiescent Crohn’s disease through comparison with paired healthy first-degree relatives using fecal metagenomics and metabolomics

2024-02-28

Abstract excerpt

Prior studies indicate no correlation between gut microbiota of healthy first-degree relatives (HFDRs) of Crohn’s disease (CD) patients and development of CD. Here, we utilized HFDRs as controls to examine the microbiota and metabolome in individuals with active (CD-A) and quiescent (CD-R) CD, thereby minimizing the influence of genetic and environmental factors. Compared to non-relative controls, the use of HFDR...

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Literature Corpus work: 671b7fd9-f3ab-58b8-a245-e91ec35e7c40
DOI: 10.1101/2024.02.24.581863

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Enhanced microbiota profiling in patients with quiescent Crohn’s disease through comparison with paired healthy first-degree relatives using fecal metagenomics and metabolomicsDOI 10.1101/2024.02.24.581863Read

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