Article
An altered endometrial CD8 tissue resident memory T cell population in recurrent miscarriage.
Scientific reports - 23 Jan 2017
Southcombe J H, Mounce G, McGee K, Elghajiji A, Brosens J, Quenby S, Child T, Granne I
Abstract excerpt
When trying to conceive 1% of couples have recurrent miscarriages, defined as three or more consecutive pregnancy losses. This is not accounted for by the known incidence of chromosomal aneuploidy in miscarriage, and it has been suggested that there is an immunological aetiology. The endometrial mucosa is populated by a variety of immune cells which in addition to providing host pathogen immunity must facilitate...
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