Article
Increase in FoxP3, CD56 immune cells and decrease in glands PGRMC1 expression in the endometrium are associated with recurrent miscarriages.
European journal of obstetrics, gynecology, and reproductive biology - 1 Feb 2020
Lyzikova Yulia Anatolievna, Zinovkin Dmitry Aleksandrovich, Pranjol Md Zahidul Islam
Abstract excerpt
OBJECTIVE: Recurrent miscarriage (RM) is a multifactorial condition that involves frequent uterine anatomical abnormalities, parental karyotype abnormalities, and clotting disorders. We investigate the potential roles of endometrium FoxP3+ Tregs and CD56+ cells (uNK cells) and endometrial expression of PGRMC1 in the development of recurrent miscarriage. STUDY DESIGN: This prospective study included 102 out of 286...
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