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Article

Unraveling the molecular mechanisms of alcohol dependence.

Trends in genetics : TIG - 1 Jan 2009

Kalsi Gursharan, Prescott Carol A, Kendler Kenneth S, Riley Brien P

Abstract excerpt

Alcohol dependence (AD) is a common, chronic, relapsing disorder. Compelling epidemiological evidence indicates that >50% of the risk for becoming alcoholic stems from genetic susceptibility and genetic studies have identified several risk genes. Alcohol intake alters gene expression patterns, thereby producing long-lasting cellular and molecular adaptations that might explain the development and maintenance of...

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Identifiers

PMID: 19010566
DOI: 10.1016/j.tig.2008.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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