Article
Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study.
The Lancet. Respiratory medicine - 1 Apr 2017
Dheda Keertan, Limberis Jason D, Pietersen Elize, Phelan Jody, Esmail Aliasgar, Lesosky Maia, Fennelly Kevin P, Te Riele Julian, Mastrapa Barbara, Streicher Elizabeth M, Dolby Tania, Abdallah Abdallah M, Ben-Rached Fathia, Simpson John, Smith Liezel, Gumbo Tawanda, van Helden Paul, Sirgel Frederick A, McNerney Ruth, Theron Grant, Pain Arnab, Clark Taane G, Warren Robin M
Abstract excerpt
BACKGROUND: The emergence of programmatically incurable tuberculosis threatens to destabilise control efforts. The aim of this study was to collect prospective patient-level data to inform treatment and containment strategies. METHODS: In a prospective cohort study, 273 South African patients with extensively drug-resistant tuberculosis, or resistance beyond extensively drug-resistant tuberculosis, were followed...
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