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Article

Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis.

Psychiatry research - 30 Mar 2015

Ahmed Anthony O, Mantini Andrew M, Fridberg Daniel J, Buckley Peter F

Abstract excerpt

Studies suggest that the BDNF Val66Met (rs6265) polymorphism is associated with the incidence of schizophrenia and neurocognitive functioning. These associations appear to be however somewhat mixed. We conducted two separate meta-analyses to investigate (1) the association between the Val66Met polymorphism and neurocognition in people with schizophrenia and (2) the association between peripheral expression of...

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Source

Identifiers

PMID: 25681004
DOI: 10.1016/j.psychres.2014.12.069

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis.PMID 25681004Read ↗

Association of the brain-derived neurotrophic factor Val66Met polymorphism with negative symptoms severity, but not cognitive function, in first-episode schizophrenia spectrum disorders.Semantic proximity Read ↗

Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphism and Risk of Schizophrenia: A Meta-analysis of Case-Control Studies.Semantic proximity Read ↗

Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls.Semantic proximity Read ↗

Impact of brain-derived neurotrophic factor genetic polymorphism on cognition: A systematic review.Semantic proximity Read ↗

A role for the BDNF gene Val66Met polymorphism in schizophrenia? A comprehensive review.Semantic proximity Read ↗

BDNF Val66Met and cognition: all, none, or some? A meta-analysis of the genetic association.Semantic proximity Read ↗

Prefrontal cognition in schizophrenia and bipolar illness in relation to Val66Met polymorphism of the brain-derived neurotrophic factor gene.Semantic proximity Read ↗

Association of the brain-derived neurotrophic factor gene G196A rs6265 polymorphisms and the cognitive function and clinical symptoms of schizophrenia.Semantic proximity Read ↗

Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers.Semantic proximity Read ↗

Genetic predisposition of BDNF (rs6265) gene is susceptible to Schizophrenia: A prospective study and updated meta-analysis.Semantic proximity Read ↗

Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder.Semantic proximity Read ↗

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