Article
Variants on chromosome 9p21.3 correlated with ANRIL expression contribute to stroke risk and recurrence in a large prospective stroke population.
Stroke - 1 Jan 2012
Zhang Weili, Chen Yu, Liu Peng, Chen Jingzhou, Song Lei, Tang Yue, Wang Yuyao, Liu Jibin, Hu Frank B, Hui Rutai
Abstract excerpt
BACKGROUND AND PURPOSE: ANRIL encodes a long antisense noncoding RNA in the INK4 locus. Although ANRIL has been proven to be associated with coronary heart disease, its roles in stroke are inconsistent, and sparse data are available regarding hemorrhagic stroke. METHODS: A Chinese case-control study was conducted, comprising 1657 cases (724 atherothrombosis, 466 lacunar infarction, and 462 hemorrhagic strokes)...
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