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Article

Recurrent Rearrangements of Human Amylase Genes Create Multiple Independent CNV Series.

Human mutation - 1 May 2017

Shwan Nzar A A, Louzada Sandra, Yang Fengtang, Armour John A L

Abstract excerpt

The human amylase gene cluster includes the human salivary (AMY1) and pancreatic amylase genes (AMY2A and AMY2B), and is a highly variable and dynamic region of the genome. Copy number variation (CNV) of AMY1 has been implicated in human dietary adaptation, and in population association with obesity, but neither of these findings has been independently replicated. Despite these functional implications, the...

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PMID: 28101908
DOI: 10.1002/humu.23182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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