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Plasma Proteomic Analysis Distinguishes Severity Outcomes of Human Ebola Virus Disease

21 Apr 2022

Abstract excerpt

As evidenced by the 2013-2016 outbreak in West Africa, Ebola virus (EBV) disease (EVD) poses a major global health threat. In this study, we characterized the plasma proteomes of 12 individuals infected with EBV, using two different LC-MS-based proteomics platforms and an antibody-based multiplexed cytokine/chemokine assay. Clear differences were observed in the host proteome between individuals who survived and...

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PMID: 35446128
DOI: 10.1128/mbio.00567-22

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