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Induced pluripotent stem cells as a cellular model for studying Down Syndrome

29 Nov 2016

Abstract excerpt

Down Syndrome (DS), or Trisomy 21 Syndrome, is one of the most common genetic diseases. It is a chromosomal abnormality caused by a duplication of chromosome 21. DS patients show the presence of a third copy (or a partial third copy) of chromosome 21 (trisomy), as result of meiotic errors. These patients suffer of many health problems, such as intellectual disability, congenital heart disease, duodenal stenosis,...

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PMID: 28096629
DOI: 10.46582/jsrm.1202009

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