Article
Selection against variants in the genome associated with educational attainment.
Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 2017
Kong Augustine, Frigge Michael L, Thorleifsson Gudmar, Stefansson Hreinn, Young Alexander I, Zink Florian, Jonsdottir Gudrun A, Okbay Aysu, Sulem Patrick, Masson Gisli, Gudbjartsson Daniel F, Helgason Agnar, Bjornsdottir Gyda, Thorsteinsdottir Unnur, Stefansson Kari
Abstract excerpt
Epidemiological and genetic association studies show that genetics play an important role in the attainment of education. Here, we investigate the effect of this genetic component on the reproductive history of 109,120 Icelanders and the consequent impact on the gene pool over time. We show that an educational attainment polygenic score, POLYEDU, constructed from results of a recent study is associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.