Article
Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology.
Neuroscience and biobehavioral reviews - 1 Mar 2017
Ahmed Rebekah M, Irish Muireann, van Eersel Janet, Ittner Arne, Ke Yazi D, Volkerling Alexander, van der Hoven Julia, Tanaka Kimi, Karl Tim, Kassiou Michael, Kril Jillian J, Piguet Olivier, Götz Jürgen, Kiernan Matthew C, Halliday Glenda M, Hodges John R, Ittner Lars M
Abstract excerpt
Frontotemporal dementia (FTD) is the second most common cause of young onset dementia. It is increasingly recognized that there is a clinical continuum between FTD and amyotrophic lateral sclerosis (ALS). At a clinical, pathological and genetic level there is much heterogeneity in FTD, meaning that our understanding of this condition, pathophysiology and development of treatments has been limited. A number of...
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