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Article

Mouse models of neurodegenerative diseases: criteria and general methodology.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Janus Christopher, Welzl Hans

Abstract excerpt

The major symptom of Alzheimer's disease is rapidly progressing dementia, coinciding with the formation of amyloid and tau deposits in the central nervous system, and neuronal death. At present familial cases of dementias provide the most promising foundation for modelling neurodegeneration. We describe the mnemonic and other major behavioral symptoms of tauopathies, briefly outline the genetics underlying...

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PMID: 20012407
DOI: 10.1007/978-1-60761-058-8_19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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