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Article

Combined core promoter mutations and pre-S deletion of HBV may not increase the risk of HCC: a geographical epidemiological study in Guangxi, China.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2013

Li Guo-Jian, Harrison Tim J, Yang Jin-Ye, Chen Qin-Yan, Wang Xue-Yan, Fang Zhong-Liao

Abstract excerpt

BACKGROUND: Although persistent hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC), the mechanisms of oncogenesis remain obscure. AIMS: To determine whether the findings that HBV basal core promoter (BCP) A1762T, G1764A double mutations, pre-S deletions and a combination of both are risk factors of HCC are supported by geographical epidemiology. METHODS: Study subjects were...

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PMID: 23517325
DOI: 10.1111/liv.12142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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