Article
Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence.
Journal of bacteriology - 1 Oct 2010
Joseph Biju, Schneiker-Bekel Susanne, Schramm-Glück Anja, Blom Jochen, Claus Heike, Linke Burkhard, Schwarz Roland F, Becker Anke, Goesmann Alexander, Frosch Matthias, Schoen Christoph
Abstract excerpt
Neisseria meningitidis serogroup B strains are responsible for most meningococcal cases in the industrialized countries, and strains belonging to the clonal complex ST-41/44 are among the most prevalent serogroup B strains in carriage and disease. Here, we report the first genome and transcriptome comparison of a serogroup B carriage strain from the clonal complex ST-41/44 to the serogroup B disease strain MC58...
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