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Article

MUC5AC enhances tumor heterogeneity in lung adenocarcinoma with mucin production and is associated with poor prognosis.

Japanese journal of clinical oncology - 10 Jun 2020

Dong Yujie, Zhou Lijuan, Zhao Dan, Li Kun, Liu Zichen, Che Nanying, Liu Honggang

Abstract excerpt

OBJECTIVE: The clinicopathological significance of Mucin5AC (MUC5AC) in lung adenocarcinoma with mucin production is still unclear. This study aimed to explore MUC5AC expression in lung adenocarcinoma with mucin production and its correlation with histological subtypes, common driver mutations and its impact on prognosis. METHODS: MUC5AC and thyroid transcription factor 1 immunohistochemistry was performed on...

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Adenocarcinoma, Mucinous
Adenocarcinoma of Lung
ErbB Receptors
Gene Expression Regulation, Neoplastic
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins p21(ras)

Thyroid Nuclear Factor 1

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PMID: 32083303
DOI: 10.1093/jjco/hyaa016

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