Article
Identification of human skeletal muscle miRNA related to strength by high-throughput sequencing.
Physiological genomics - 1 Jun 2018
Mitchell Cameron J, D'Souza Randall F, Schierding William, Zeng Nina, Ramzan Farha, O'Sullivan Justin M, Poppitt Sally D, Cameron-Smith David
Abstract excerpt
The loss of muscle size, strength, and quality with aging is a major determinant of morbidity and mortality in the elderly. The regulatory pathways that impact the muscle phenotype include the translational regulation maintained by microRNAs (miRNA). Yet the miRNAs that are expressed in human skeletal muscle and relationship to muscle size, strength, and quality are unknown. Using next-generation sequencing, we...
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