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Article

Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal Cancer.

Cell reports - 3 Jan 2017

Cristobal Alba, van den Toorn Henk W P, van de Wetering Marc, Clevers Hans, Heck Albert J R, Mohammed Shabaz

Abstract excerpt

Diseases at the molecular level are complex and patient dependent, necessitating development of strategies that enable precision treatment to optimize clinical outcomes. Organoid technology has recently been shown to have the potential to recapitulate the in vivo characteristics of the original individual's tissue in a three-dimensional in vitro culture system. Here, we present a quantitative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28052255
DOI: 10.1016/j.celrep.2016.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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