Article

Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates

2022-03-07

Abstract excerpt

<h4>Background: </h4> Colon cancer is the third most common cancer and second highest cause of cancer deaths worldwide. The aim of the study was to find new biomarkers for diagnosis, prognosis and therapeutic drug targets for this disease. <h4>Methods: </h4>: Four low-grade and four high-grade human colon adenocarcinoma tumours with patient-matched normal colon tissues were analysed. Additionally, tissue-derived p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ec1ec31-2535-5f7a-83f6-e7cb9ab79908
DOI: 10.21203/rs.3.rs-1420689/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidatesDOI 10.21203/rs.3.rs-1420689/v1Read

Colorectal cancer atlas: An integrative resource for genomic and proteomic annotations from colorectal cancer cell lines and tissues.Semantic proximity Read

Development and validation of a ferroptosis-related lncRNAs prognosis signature in colon cancerSemantic proximity Read

OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stagesSemantic proximity Read

Molecular characterization of colorectal mucinous adenocarcinoma and adenocarcinoma, not otherwise specified, identified by multiomic data analysisSemantic proximity Read

Transcriptome-Wide Analysis and Experimental Validation from FFPE Tissue Identifies Stage-Specific Gene Expression Profiles Differentiating Adenoma, Carcinoma In-Situ and Adenocarcinoma in Colorectal Cancer ProgressionSemantic proximity Read

An eight ferroptosis-related lncRNA signature predicts the survival of patients with colon adenocarcinomaSemantic proximity Read

A ferroptosis-related lncRNAs signature for prognosis prediction and its relationship with immune microenvironment in colon adenocarcinomaSemantic proximity Read

Integrative Machine Learning Reveals Potential Signature Genes Using Transcriptomics in Colon CancerSemantic proximity Read

Expression and Prognostic Characteristics of Ferroptosis-Related Genes in Colon CancerSemantic proximity Read

Identification of distinctive protein expression patterns in colorectal adenomaSemantic proximity Read

Transcriptome-based identification of molecular markers related to the development and prognosis of Colon cancerSemantic proximity Read

Establishment and characterization of a novel cell line (cc‑006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient.Semantic proximity Read