Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue.

Cell reports - 3 Jan 2017

Sanyal Abhishek, Naumann Jennifer, Hoffmann Linda Sarah, Chabowska-Kita Agnieszka, Ehrlund Anna, Schlitzer Andreas, Arner Peter, Blüher Matthias, Pfeifer Alexander

Abstract excerpt

Current worldwide figures suggest that obesity is pandemic. Understanding the underlying molecular mechanisms would help develop viable anti-obesity therapies. Here, we assess the influence of obesity-induced inflammation on white adipocyte cyclic guanosine monophosphate (cGMP) signaling, which is beneficial for adipocyte differentiation and thermogenesis. We find that murine gonadal and not inguinal fat is prone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipogenesis
Share to Adipose Tissue, White

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Cyclic GMP-Dependent Protein Kinases

Share to Gonads

Share to Guanylate Cyclase

Share to Mice, Obese

Share to Solubility

Source

Identifiers

PMID: 28052251
DOI: 10.1016/j.celrep.2016.12.028

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue.PMID 28052251Read ↗

The Interplay between Obesity and InflammationSemantic proximity Read ↗

Role of microRNAs on adipogenesis, chronic low-grade inflammation, and insulin resistance in obesitySemantic proximity Read ↗

The Impact of Obesity-Related Genetic Variants on NF-κB Signaling in Cardiovascular Disease: A Systematic ReviewSemantic proximity Read ↗

STAT1 dissociates adipose tissue inflammation from insulin sensitivity in obesitySemantic proximity Read ↗

Neuroinflammatory basis of metabolic syndromeSemantic proximity Read ↗

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice.Semantic proximity Read ↗

Depletion of regulator-of-G-protein signaling-10 in mice exaggerates high-fat diet-induced insulin resistance and inflammation, and this effect is mitigated by dietary green tea extract.Semantic proximity Read ↗

Metabolic benefits of inhibition of p38α in white adipose tissue in obesity.Semantic proximity Read ↗

Signaling pathways linking inflammation to insulin resistanceSemantic proximity Read ↗

SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammationSemantic proximity Read ↗

Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditionsSemantic proximity Read ↗

Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.