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Article

The hypoparathyroidism-associated mutation in Drosophila Gcm compromises protein stability and glial cell formation.

Scientific reports - 4 Jan 2017

Xi Xiao, Lu Lu, Zhuge Chun-Chun, Chen Xuebing, Zhai Yuanfen, Cheng Jingjing, Mao Haian, Yang Chang-Ching, Tan Bertrand Chin-Ming, Lee Yi-Nan, Chien Cheng-Ting, Ho Margaret S

Abstract excerpt

Differentiated neurons and glia are acquired from immature precursors via transcriptional controls exerted by factors such as proteins in the family of Glial Cells Missing (Gcm). Mammalian Gcm proteins mediate neural stem cell induction, placenta and parathyroid development, whereas Drosophila Gcm proteins act as a key switch to determine neuronal and glial cell fates and regulate hemocyte development. The...

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Identifiers

PMID: 28051179
DOI: 10.1038/srep39856
PMCID: PMC5209662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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