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Article

Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2017

Fujii Masanori

Abstract excerpt

Atopic dermatitis (AD) is a common pruritic chronic skin disease. AD pathogenesis remains elusive, but may involve complex interplays among skin barrier dysfunction, Th2 inflammation, and pruritus. Current treatments for AD are still limited to symptomatic therapies. We previously showed that HR-1 hairless mice fed a special diet (HR-AD) develop AD-like symptoms; however, the ingredient(s) causing dermatitis...

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Identifiers

PMID: 28049895
DOI: 10.1248/yakushi.16-00200

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