Article
Resolvase OsGEN1 Mediates DNA Repair by Homologous Recombination.
Plant physiology - 1 Feb 2017
Wang Chong, Higgins James D, He Yi, Lu Pingli, Zhang Dabing, Liang Wanqi
Abstract excerpt
Yen1/GEN1 are canonical Holliday junction resolvases that belong to the RAD2/XPG family. In eukaryotes, such as budding yeast, mice, worms, and humans, Yen1/GEN1 work together with Mus81-Mms4/MUS81-EME1 and Slx1-Slx4/SLX1-SLX4 in DNA repair by homologous recombination to maintain genome stability. In plants, the biological function of Yen1/GEN1 remains largely unclear. In this study, we characterized the loss of...
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