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Article

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks.

Cell metabolism - 7 Feb 2017

Akerman Ildem, Tu Zhidong, Beucher Anthony, Rolando Delphine M Y, Sauty-Colace Claire, Benazra Marion, Nakic Nikolina, Yang Jialiang, Wang Huan, Pasquali Lorenzo, Moran Ignasi, Garcia-Hurtado Javier, Castro Natalia, Gonzalez-Franco Roser, Stewart Andrew F, Bonner Caroline, Piemonti Lorenzo, Berney Thierry, Groop Leif, Kerr-Conte Julie, Pattou Francois, Argmann Carmen, Schadt Eric, Ravassard Philippe, Ferrer Jorge

Abstract excerpt

Recent studies have uncovered thousands of long non-coding RNAs (lncRNAs) in human pancreatic β cells. β cell lncRNAs are often cell type specific and exhibit dynamic regulation during differentiation or upon changing glucose concentrations. Although these features hint at a role of lncRNAs in β cell gene regulation and diabetes, the function of β cell lncRNAs remains largely unknown. In this study, we...

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Identifiers

PMID: 28041957
DOI: 10.1016/j.cmet.2016.11.016
PMCID: PMC5300904

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PDX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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