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Article

Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility

1 Jul 2014

Abstract excerpt

Type 2 diabetes usually ensues from the inability of pancreatic beta cells to compensate for incipient insulin resistance. The loss of beta cell mass, function, and potentially beta cell identity contribute to this dysfunction to extents which are debated. In recent years, long non-coding RNAs (lncRNAs) have emerged as potentially providing a novel level of gene regulation implicating critical cellular processes...

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PMID: 25071823
DOI: 10.3389/fgene.2014.00193

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