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Article

Outcome of 24 years national surveillance in different hereditary colorectal cancer subgroups leading to more individualised surveillance.

Journal of medical genetics - 1 May 2017

Lindberg Lars Joachim, Ladelund Steen, Frederiksen Birgitte Lidegaard, Smith-Hansen Lars, Bernstein Inge

Abstract excerpt

BACKGROUND: Individuals with hereditary non-polyposis colorectal cancer (HNPCC) have a high risk of colorectal cancer (CRC). The benefits of colonic surveillance in Lynch syndrome and Amsterdam-positive (familial CRC type X familial colorectal cancer type X (FCCTX)) families are clear; only the interval between colonoscopies is debated. The potential benefits for families not fulfilling the Amsterdam criteria are...

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PMID: 28039328
DOI: 10.1136/jmedgenet-2016-104284

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