Article
Increased colorectal cancer risk in first-degree relatives of patients with hyperplastic polyposis syndrome.
Gut - 1 Sept 2010
Boparai K S, Reitsma J B, Lemmens V, van Os T A M, Mathus-Vliegen E M H, Koornstra J J, Nagengast F M, van Hest L P, Keller J J, Dekker E
Abstract excerpt
INTRODUCTION: Hyperplastic polyposis syndrome (HPS) is characterised by the presence of multiple colorectal hyperplastic polyps and is associated with an increased colorectal cancer (CRC) risk. For first-degree relatives of HPS patients (FDRs) this has not been adequately quantified. Reliable evidence concerning the magnitude of a possible excess risk is necessary to determine whether preventive measures, like...
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