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Detection of the DNA methylation of seven genes contribute to the early diagnosis of lung cancer

5 Feb 2024

Abstract excerpt

BACKGROUND: Low-dose Computed Tomography (CT) is used for the detection of pulmonary nodules, but the ambiguous risk evaluation causes overdiagnosis. Here, we explored the significance of the DNA methylation of 7 genes including TAC1, CDO1, HOXA9, ZFP42, SOX17, RASSF1A and SHOX2 in the blood cfDNA samples in distinguishing lung cancer from benign nodules and healthy individuals. METHOD: A total of 149 lung cancer...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38315228
DOI: 10.1007/s00432-023-05588-z

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