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Article

High endothelial venules associated with T cell subsets in the inflamed gut of newly diagnosed inflammatory bowel disease patients.

Clinical and experimental immunology - 1 Apr 2017

Horjus Talabur Horje C S, Smids C, Meijer J W R, Groenen M J, Rijnders M K, van Lochem E G, Wahab P J

Abstract excerpt

Naive and central memory T lymphocytes (TN and TCM ) can infiltrate the inflamed gut mucosa in inflammatory bowel disease (IBD) patients. Homing of these subsets to the gut might be explained by ectopic formation of tertiary lymphoid organs (TLOs), containing high endothelial venules (HEVs). We aimed to evaluate the presence of HEVs and TLOs in inflamed intestinal mucosa of newly diagnosed, untreated IBD patients...

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Identifiers

PMID: 28033681
DOI: 10.1111/cei.12918
PMCID: PMC5343347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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