Article
Two Distinctive Phenotypes of AcMNPV Display Different Immune Abilities and Intracellular Destiny.
PloS one - 1 Jan 2016
Molina Guido N, Tavarone Eugenia, Taboga Oscar, Molinari Paula
Abstract excerpt
The budded phenotype (BV) of the baculovirus AcMNPV has been demonstrated to have strong immunostimulatory properties that are relevant for the development of vaccines and antiviral therapies. Although the occluded phenotype (ODV) shares the main structural proteins and its genome with BV, it has been poorly studied in mammals. In this study, we assessed the capacity of ODV to induce immune responses in mice. In...
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