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Article

Detection of ALK rearrangements in lung cancer patients using a homebrew PCR assay.

Oncotarget - 31 Jan 2017

Yu Hui, Chang JianHua, Liu Fang, Wang Qifeng, Lu YongMing, Zhang ZhuanXu, Shen Jiabing, Zhai Qing, Meng Xia, Wang Jialei, Ye Xun

Abstract excerpt

Lung cancer patients with anaplastic lymphoma kinase (ALK) rearrangements are candidates for targeted therapeutics. However, patients must be tested with a companion diagnostic assay to realize their ALK rearrangement status. We analyzed the publicly available E-GEOD-31210 microarray dataset and identified a non-coding RNA, sweyjawbu, which is strongly associated with ALK rearrangements. We validated these...

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Share to Anaplastic Lymphoma Kinase
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Gene Rearrangement

Share to Predictive Value of Tests

Share to Real-Time Polymerase Chain Reaction

Share to Receptor Protein-Tyrosine Kinases

Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 28032602
DOI: 10.18632/oncotarget.13886
PMCID: PMC5352355

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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