Article
Association Between Geranylgeranyl Pyrophosphate Synthase Gene Polymorphisms and Bone Phenotypes and Response to Alendronate Treatment in Chinese Osteoporotic Women.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 20 Mar 2016
Han Lan-Wen, Ma Dou-Dou, Xu Xiao-Jie, Lü Fang, Liu Yi, Xia Wei-Bo, Jiang Yan, Wang Ou, Xing Xiao-Ping, Li Mei
Abstract excerpt
Objective To investigate the relationship between geranylgeranyl pyrophosphate synthase (GGPPS) gene polymorphisms and bone response to alendronate in Chinese osteoporotic women.Methods A total of 639 postmenopausal women with osteoporosis or osteopenia were included and randomly received treatment of low dose (70 mg per two weeks) or standard dose (70 mg weekly) of alendronate for one year. The six tag single...
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